ECOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE Parkinson’s disease and Lewy body dementia belong to a family of neurodegenerative disorders called synucleinopathies because they are caused by the pathological accumulation of protein alpha-synuclein into structures called Lewy bodies and Lewy neurites in the brain. In a healthy brain, alpha-synuclein is found in synapses as distinct proteins called...