Schematic representation of the eight clinical domains covered by the 2023 recommendations. Note that severe prognosis is not represented. The different shades of green boxes labelled A–D represent the Strength of the Recommendation (SoR) as shown in the relative column of table 1. Dotted lines connect same drug or drug class across distinct clinical domains....
Tag: <span>systemic sclerosis</span>
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Systemic sclerosis research finds protein TLR8 influences the production of disease-related cytokines
September 23, 2024 by Jan Grabowski, TWINCORE – Zentrum für Experimentelle und Klinische Infektionsforschung TLR8 is expressed in monocytes and cDCs but not pDCs of patients with systemic sclerosis (SSc). Credit: Arthritis & Rheumatology (2024). DOI: 10.1002/art.42964Systemic sclerosis is an autoimmune disease that primarily causes inflammation of the skin, as well as internal organs such...
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Antioxidant Dietary Supplement “Twendee X®” can help counter systemic sclerosis
NEWS RELEASE 17-MAY-2024 Study finds the supplement effective in inhibiting fibrosis and suppressing disease activity and progression of systemic sclerosis, an intractable disease Peer-Reviewed PublicationLOUIS PASTEUR CENTER FOR MEDICAL RESEARCH OXIDATIVE STRESS IS KNOWN TO EXACERBATE FIBROSIS AND AUTOIMMUNITY. IN A NEW STUDY, RESEARCHERS FROM JAPAN HAVE INVESTIGATED THE EFFECTS OF A DIETARY ANTIOXIDANT SUPPLEMENT...
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Hippo signaling pathway gives new insight into systemic sclerosis
by Valerie Goodwin, University of Michigan Credit: Jacob Dwyer, Justine Ross / Michigan MedicineSystemic sclerosis causes the skin to tighten and harden resulting in a potentially fatal autoimmune condition that is associated with lung fibrosis and kidney disease. University of Michigan Health researchers have studied the pathology of systemic sclerosis to understand better the disease and...
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Researchers identify incidence and risk factors for new-onset interstitial lung disease in systemic sclerosis
by American College of Rheumatology Credit: Pixabay/CC0 Public Domain New research at ACR Convergence 2023, the American College of Rheumatology’s (ACR) annual meeting, reports the incidence and risk factors for new-onset interstitial lung disease (ILD) in previously ILD-negative systemic sclerosis patients. Interstitial lung disease is a common complication and cause of death in systemic sclerosis (SSc,...
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Non-pharmacological management for systemic lupus erythematosus and systemic sclerosis
by European Alliance of Associations for Rheumatology, EULAR Credit: Unsplash/CC0 Public Domain Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by multisystem involvement. Systemic sclerosis (SSc) or scleroderma is another rheumatic autoimmune disease that affects blood vessels, skin, and visceral organs. EULAR has previously published recommendations for the management of these two conditions...