Tag: <span>systemic</span>

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Cognitive behavioral therapy delivered electronically more effective than face-to-face, says researchers
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Cognitive behavioral therapy delivered electronically more effective than face-to-face, says researchers

by McMaster University Cognitive behavioral therapy delivered electronically to treat people with depression is more effective than face to face, suggests an evidence review led by McMaster University. Based on randomized control trials, the systematic review and analysis revealed that cognitive behavioral therapy that connected therapists and patients through such modes as web-based applications, video-conferencing,...

Reactive arthritis is fueled by amyloid protein during salmonella infection
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Reactive arthritis is fueled by amyloid protein during salmonella infection

by Temple University Like the infrastructure of an apartment building, a fibrous protein known as curli amyloid that is produced by bacteria provides the supportive framework for biofilms—thick extracellular substances made by bacteria that enable multiple bacterial cells to assemble, survive, and thrive together. Curli amyloid, however, is also a key factor in diarrheal illness...

Age-related impairments reversed in animal model
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Age-related impairments reversed in animal model

by University of Bern With age the frequency of adipose tissue eosinophils decreases gradually. This leads to the production of inflammatory mediators, which promote age-related impairments (e.g. frailty and immunosenescence). Eosinophil cell transfers increase the frequency of these cells in adipose tissue and dampen age-related chronic low-grade inflammation. This results in systemic rejuvenation of the...

Antibodies against phosphorylcholine give protection against rheumatic systemic disease
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Antibodies against phosphorylcholine give protection against rheumatic systemic disease

by Karolinska Institutet A novel study from the Institute of Environmental Medicine at Karolinska Institutet indicates that antibodies against a small lipid entity, phosphorylcholine (PC), can be associated with protection in inflammatory systemic diseases, including SLE and Sjögren’s syndrome. The results support evidence for a potential treatment by providing antibodies (anti-PC) to patients with these...

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Novel compound shows promise for ANCA-associated vasculitis

Reviewed by Emily Henderson, B.Sc. ANCA-associated vasculitis (AAV) is a systemic disease involving the formation of special autoantibodies (so-called anti-neutrophil cytoplasmic antibodies/ANCA) and vascular inflammation. There are several diseases associated with involvement of the kidneys, lungs, upper respiratory tract, heart, skin and the nervous system; potentially life-threatening courses of disease are also possible. Immunosuppressive therapy...

Study suggests nicotine exposure alone leads to pulmonary hypertension
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Study suggests nicotine exposure alone leads to pulmonary hypertension

by Louisiana State University A study conducted by a team of researchers at LSU Health New Orleans has shown for the first time that chronic exposure to inhaled nicotine alone increases blood pressure (hypertension), in both the body’s general circulation and in the lungs that can lead to pulmonary hypertension. The study also found that...

Light helps arthritis treatments target joints
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Light helps arthritis treatments target joints

CREDIT: VICTORIA WICKENHEISSER Bethesda, MD – Although today’s rheumatoid arthritis treatments can reduce symptoms, they often come with serious side effects. Results from a new mouse study suggest that a new light-activated drug delivery method helps confine treatments to the joints, which could reduce whole-body side effects. In the U.S., 1.3 million people are currently...

For ME/CFS patients, viral immunities come at a devastating, lifelong cost
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For ME/CFS patients, viral immunities come at a devastating, lifelong cost

by University of California – San Diego Mylagic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disabling and complex illness. Affected persons often cannot pursue ordinary activities—physical or mental—because of an incapacitating loss of energy and other symptoms, and may find themselves confined to bed or house-bound for years. Anyone can develop ME/CFS, though it most commonly...

Blood test may help doctors catch pancreatic cancer early
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Blood test may help doctors catch pancreatic cancer early

By PENN MEDICINE PHILADELPHIA – A blood test may be able to detect the most common form of pancreatic cancer while it is still in its early stages while also helping doctors accurately stage a patient’s disease and guide them to the appropriate treatment. A multidisciplinary study from the University of Pennsylvania found the test...

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New two-in-one powder aerosol to upgrade fight against deadly superbugs in lungs

Purdue University researchers have developed a new approach to treating the fourth-leading cause of death worldwide – lower respiratory infections. Lung infections, often caused by multi-drug-resistant bacteria, are deadly because the ‘superbugs’ are resistant to all available antibiotics. Even worse, traditional systemic administrations of those antibiotics cannot reach the lung surface to kill the bacteria,...

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