Tag: <span>systolic and diastolic</span>

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Urocortin 3 gene therapy increases systolic and diastolic function in heart failure

New Rochelle, NY, November 14, 2018–Mice with heart failure that were treated with AAV8-based gene therapy to deliver the protein urocortin 3 (UCn3) had increased blood levels of UCn3 over a 5-week period and improved heart function. The mice received a single injection of AAV8.UCn3 after cryoinjury to induce left ventricular heart failure and showed...