by Latrobe University Thymic cortical T cell deletion induced by a CDR3 cysteine. TCR-retrogenic mice expressing the 6218 or 6218αC TCR were made as described in Fig. 1, except that all recipients were male B6 mice (n = 4 for 6218; n = 4 for 6218αC). TCR-retrogenic mice were analyzed 5 weeks after BM transfer at 99-138 days of age....
by University of Michigan A compilation of brain images from the study of obsessive-compulsive disorder treatment response and its correlation with activation during cognitive and reward processing tasks. Credit: University of Michigan New research could improve the odds that people with obsessive-compulsive disorder will receive a therapy that really works for them—something that eludes more...
When bacteria or viruses enter the body, proteins on their surfaces are recognized and processed to activate T cells, white blood cells with critical roles in fighting infections. During T-cell activation, a molecular complex known as the microtubule-organizing center (MTOC) moves to a central location on the surface of the T-cell. Microtubules have several important...
