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Major genetic study reveals unexpectedly high variation in T-cell receptor genes between persons
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Major genetic study reveals unexpectedly high variation in T-cell receptor genes between persons

by Karolinska Institutet Graphical Abstract. Credit: Immunity (2023). DOI: 10.1016/j.immuni.2023.01.026 T-cells that are part of our immune system are central in the protection against infections and cancer. With the help of TCRs, the cells recognize foreign invaders and tumor cells. “It was previously unknown how variable human TCR genes are,” says Gunilla Karlsson Hedestam, professor at the...

The global race for a T cell receptor that zeros in on—and annihilates—solid tumors
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The global race for a T cell receptor that zeros in on—and annihilates—solid tumors

by Delthia Ricks , Medical Xpress Credit: CC0 Public Domain Immunobiologists in China have designed a synthetic T cell receptor for anticancer therapy, engineering the protein not only with a capability to seek and destroy solid tumors, but endowing this cancer fighting weapon with potent endurance to get the job done. So far, the Beijing-based research has...