by Cold Spring Harbor Laboratory Credit: CC0 Public Domain T cells are a special class of white blood cells that patrol the body and attack infected or foreign tissue. They learn to distinguish friendly proteins from dangerous ones in an organ called the thymus. However, when T cells mistakenly identify healthy proteins as foreign, it can...
by Leiden University Credit: CC0 Public Domain A COVID-19 vaccine that specifically instructs the immune system to produce T-cells rather than antibodies is shown to provide good protection in a mouse model, Leiden University Medical Center (LUMC) researchers report in Nature Communications. According to them, the alternative vaccine may offer a solution for people with a...
by La Jolla Institute for Immunology This image captures intraepithelial T cells (blue dots) and collagen in the basement membrane (green). This view shows how the cells and the basement membrane are connected. The black space is not empty—it is filled with cells in the intestinal villus, but they were not labeled with fluorescent antibodies so...
by Peter Doherty Institute for Infection and Immunity Credit: Nature Immunology (2022). DOI: 10.1038/s41590-022-01273-4. https://www.nature.com/articles/s41590-022-01273-4 Researchers at the Peter Doherty Institute for Infection and Immunity (Doherty Institute) have identified how to increase the ability of tissue-resident memory T (TRM) cells to help fight viral infections and certain cancers. This discovery adds to the growing knowledge around the huge...
by Ludwig Maximilian University of Munich Scanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAID The research group led by immunologists Vigo Heissmeyer and Taku Ito-Kureha of LMU and Helmholtz Munich has revealed the essential function of m6A modifications in T...
by Sarah Williams, Gladstone Institutes Scanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAID When faced with a formidable foe for months on end, the immune system’s T cells begin to tire. Whether fighting a cancer or a chronic infection, they become...
by Perelman School of Medicine at the University of Pennsylvania Credit: CC0 Public Domain The protein TCF-1 enables various parts of otherwise insulated DNA segments to intermingle in a way that is required for the development of T cells—a key element of the body’s immune system—and the role this protein plays in T cell creation...
by Bill Hathaway, Yale University Credit: CC0 Public Domain T cells, biology textbooks teach us, are the soldiers of the immune system, constantly on the ready to respond to a variety of threats, from viruses to tumors. However, without rest and maintenance T cells can die and leave their hosts more susceptible to pathogens, Yale...
by University of Chicago Medical Center Scanning electron micrograph of human T lymphocyte or T cell. Credit: NIAID/NIH Over the past decade, researchers have made great strides in the development and administration of cancer immunotherapies, which use the body’s own immune system to treat disease. However, the therapies don’t work for every person or with...
by Bob Yirka, Medical Xpress Credit: Science (2022). DOI: 10.1126/science.abl3855 A team of researchers from Genetch, Inc., the Howard Hughes Medical Institute and the Peter MacCallum Cancer Center, has found that cancerous tumor cells are able to survive attacks by repairing holes in their membranes caused by a protein released from T cells. In their paper published...
