Tag: <span>T-gene</span>

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How a thieving transcription factor dominates the genome

One powerful DNA-binding protein, the transcription factor PU.1, steals away other transcription factors and recruits them for its own purposes, effectively dominating gene regulation in developing immune cells, according to a new Caltech-led study. The research was conducted in the laboratory of Ellen Rothenberg, Albert Billings Ruddock Professor of Biology. A paper describing the work appears in...