TOKYO MEDICAL AND DENTAL UNIVERSITY IMAGE: TAKAHASHI ET AL. SHOW THAT TGF-Β GENERATES A POPULATION OF CANCER CELLS UNDER CELL CYCLE ARREST IN G1 PHASE WITH HIGH MOTILITY BY INDUCING UNIQUE SLUG/HMGA2-INDEPENDENT EPITHELIAL-MESENCHYMAL TRANSITION (EMT). THIS LEADS TO TUMOR PROGRESSION AND POOR PROGNOSIS FOR PATIENTS WITH HEAD AND NECK CANCER. CREDIT: DEPARTMENT OF BIOCHEMISTRY, TMDU...
