Scientists at the University of Virginia and elsewhere have mapped out how the body transports testosterone, and their surprising findings may explain low testosterone levels seen in men with diabetes or patients on certain medications. The discovery allows scientists to understand exactly how testosterone, the male sex hormone, binds to a protein called serum albumin...
Tag: <span>testosterone</span>
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Testosterone slows prostate cancer recurrence in low-risk patients
In the largest such study so far undertaken, US researchers have shown that testosterone replacement slows the recurrence of prostate cancer in low-risk patients. This may call into question the general applicability of Nobel-Prize winning hormonal prostate treatment. The work is presented at the European Association of Urology congress in Barcelona. Doctors have long regarded testosterone as a hormone which promotes prostate cancer. The 1941 work of Huggins and Hodges won Huggins...
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Could higher levels of testosterone hold the key to slower aging?
A new study of older men carried out by The University of Western Australia has found there is a link between men who have higher levels of the sex hormone estradiol, produced from testosterone, and slower ageing. Ball-and-stick model of the testosterone molecule, C19H28O2, as found in the crystal structure of testosterone monohydrate. Credit: Ben...
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Testosterone replacement therapy may slow the progression of COPD
GALVESTON, Texas -Researchers from The University of Texas Medical Branch at Galveston found that testosterone replacement therapy may slow disease progression of a chronic obstructive pulmonary disease. The paper is currently available in Chronic Respiratory Disease. Chronic obstructive pulmonary disease, or COPD, is predicted by the World Health Organization to be the third-leading cause of...
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Testosterone research brings new hope for cancer patients
TEXAS A&M UNIVERSITY Many cancer patients suffer from a loss of body mass known as cachexia. Approximately 20 percent of cancer-related deaths are attributed to the syndrome of cachexia, which in cancer patients is often characterized by a rapid or severe loss of fat and skeletal muscle. Dr. Melinda Sheffield-Moore, professor and head of the...
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Experts issue recommendations to improve testosterone prescribing practices
New scientific evidence has strengthened the case for reserving testosterone therapy for well-documented cases of hypogonadism, a condition where the body does not produce enough testosterone, Endocrine Society experts concluded in an updated Clinical Practice Guideline released today. The guideline, entitled “Testosterone Therapy in Men with Hypogonadism: An Endocrine Society Clinical Practice Guideline,” was published...
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Stem cell strategy for boosting testosterone levels tested in rodents
Male hypogonadism is a condition that diminishes testosterone levels in approximately 30% of older men, but currently available therapies can produce serious side effects. In a study published December 22 in Stem Cell Reports, researchers developed an alternative approach involving the direct conversion of adult skin cells into functional testosterone-producing cells. When transplanted into male rodents...
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Scientists use stem cells to restore testosterone
Male hypogonadism is a condition affecting almost a third of the elderly male population. The most common treatment option is testosterone replacement therapy, but the practice can have significant side effects. A new development in stem cell research suggests an alternative treatment for hypogonadism may soon become available. Stem cell research may provide an alternative...