Th17-cell differentiation. Satb1 is dispensable for the differentiation of Th17 cells but plays a pivotal role in the effector functions of pathogenic Th17 cells. EurekAlert! An international study group led by researchers from Osaka University identifies a protein regulator responsible for inducing the pathogenic properties of Th17 cells, leading to multiple sclerosis and other inflammatory...
Tag: <span>Th17 cells</span>
Post
Th17 cells could facilitate wider clinical use of adoptive immunotherapy
CD8+ T cells and Th1 cells become exhausted and lose antitumor efficacy as they’re expanded for adoptive cell therapy. Th17 cells are resistant to degradation (senescence) and retain their antitumor efficacy, resulting in large numbers of …more Medical University of South Carolina (MUSC) investigators report that long-term expansion protocols for adoptive cancer immunotherapy do not...