by Medical University of Vienna Immunofluorescence staining makes granulomas glow red with a green border (macrophages with fibroblasts). Credit: MedUni Vienna/Anna RedlA research team led by Georg Stary (Medical University of Vienna and CeMM) has identified a new approach to treating the inflammatory disease sarcoidosis. In a clinical study, the inhibition of a specific signaling pathway...
by Leibniz Research Centre for Working Environments and Human Factors in Dortmund EDI3 expression and enzyme activity according to HER2 and ER status. A, EDI3 (GPCPD1; 224826_at) mRNA expression was compared among subtypes defined according to HER2 and ER status in human breast cancer Affymetrix datasets (total n = 540). B, EDI3 protein expression in breast cancer subtypes using...
by University of California, Irvine Credit: iScience (2022). DOI: 10.1016/j.isci.2022.105901 A novel peptide designed by University of California, Irvine researchers has been found to suppress the damaging lung inflammation seen in acute respiratory distress syndrome, or ARDS. The study, which appears in iScience, describes the first specific treatment designed to prevent the deadly disease, which can appear in patients with...
by Nanyang Technological University The therapeutic approach developed by NTU Singapore starts with an injection of a specially developed hydrogel using an insulin needle, into a fat deposit directly under the skin. After the hydrogel is injected, near infrared light is then shone on the site of injection. This activates the gel’s fat-burning ability. Credit:...
INSTITUTE FOR RESEARCH IN BIOMEDICINE (IRB BARCELONA) IMAGE: GENERAL OVERVIEW OF ALL PAIRWISE INTRACHROMOSOMAL RELATIONSHIPS BETWEEN LNCRNAS OF THE STUDIED SPECIES. CREDIT: IRB BARCELONA Barcelona, 16 December, 2021- Fungi of the Candida genus cause diseases such as vaginal candidiasis (highly prevalent but not serious) and systemic candidiasis (rare but can be fatal in immunocompromised patients). Although some...
MINNEAPOLIS/ST. PAUL (10/19/2021) – Recent studies may point towards a new therapeutic mechanism for a type of heart failure that currently has no specific treatment option. Researchers from the University of Minnesota Medical School — along with the University of Vermont and the Medical University of South Carolina — looked into a condition called heart failure with...
ELSEVIER IMAGE: : RUNX1 INHIBITION COMBINED WITH ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR (ANTI-VEGF) THERAPY ACHIEVES BETTER CONTROL OF EXPERIMENTAL CHOROIDAL NEOVASCULARIZATION ACTIVITY COMPARED TO MONOTHERAPY. CREDIT: THE AMERICAN JOURNAL OF PATHOLOGY Philadelphia, February 22, 2021 – Runt-related transcription factor 1 (RUNX1) has been linked to retinal neovascularization and the development of abnormal blood vessels, which result...
Vanderbilt researchers—including Charles Sanders, associate dean for research and professor of biochemistry, and graduate student Justin Marinko—have illuminated the cause of Charcot-Marie-Tooth disease, putting them on the road to developing therapeutic approaches for the disease that affects one in 2,500 people. The discovery was published in the article “Direct Relationship Between Increased Expression and Mistrafficking of the Charcot-Marie-Tooth-Associated Protein PMP22” published in...
Using the Canadian Light Source (CLS) at the University of Saskatchewan, Marta Cerruti, an Associate Professor in McGill’s Department of Materials Engineering, and her team analyzed damaged heart valves from patients who had undergone transplants. Their findings, recently published in Acta Biomaterialia, show considerable differences in the mineral deposits found in aortic valves of men...
by Helmholtz Association of German Research Centres Researchers at Helmholtz Zentrum München, Technical University of Munich (TUM) and the German Center for Infection Research (DZIF) have developed a novel therapeutic approach to cure chronic hepatitis B. The scientists found that the large amount of hepatitis B virus proteins expressed in the liver prevents the body’s...
