by University of Texas Health Science Center at Houston Credit: Pixabay/CC0 Public Domain A newly developed agonistic antibody reduced the amyloid pathology in mice with Alzheimer’s disease, signaling its promise as a potential treatment for the disease, according to a team of researchers at UTHealth Houston. Research led by senior author Zhiqiang An, Ph.D., professor...
UNIVERSITY OF TSUKUBA Tsukuba, Japan—Aging is universal. Both osteoporosis and the bone fractures that occur as a result of osteoporosis become more likely with age. Current clinical guidelines do not recommend bed rest during treatment for osteoporotic vertebral fractures—spinal fractures that occur in bones that has been weakened by osteoporosis—because there has not been enough...
NATIONAL RESEARCH COUNCIL OF SCIENCE & TECHNOLOGY IMAGE: Schematic illustration of preferential immune responses during the cancer-activated DOX prodrug nanoparticle (CAP-NPS)-based chemotherapy: CAP-NPs exhibit selective tumor accumulation via enhanced permeability and retention (EPR) effect and cancer cell-specific activation by overexpressed cancer-associated cathepsin B. Consequently, CAP-NPs selectively initiate enhanced immunogenic cell death (ICD) in cancer cells...
