by Thomas Deane, Trinity College Dublin Credit: CC0 Public Domain Researchers from Trinity have discovered a key mechanism underlying bacterial skin colonisation in atopic dermatitis, which affects millions around the globe. Atopic dermatitis (AD, also called commonly eczema) is the most common chronic inflammatory skin disorder in children, affecting 15-20% of people in childhood. During disease flares, patients experience...
by Trinity College Dublin Dr Achilleas Floudas, front right, and Professor Ursula Fearon, left, with members of Trinity College Dublin’s Molecular Rheumatology Group. A collaborative team of scientists has pinpointed two new potential therapeutic targets for rheumatoid arthritis—a painful inflammatory disease that affects an estimated 350 million people worldwide. Rheumatoid arthritis (RA) is the most common...
by Walter and Eliza Hall Institute of Medical Research Targeting a “cell survival” protein could be a valuable new approach to treating certain blood cancers associated with Epstein-Barr virus (EBV), according to research resulting from a collaboration between scientists at the Walter and Eliza Hall Institute, Australia and the University of Birmingham, UK. The research team discovered that the protein BCL-XL...
ROCKEFELLER UNIVERSITY PRESS Researchers at the University of Toronto have identified a key protein that supports the growth of many colorectal cancers. The study, which will be published December 27 in the Journal of Cell Biology, reveals that a protein called Importin-11 transports the cancer-causing protein βcatenin into the nucleus of colon cancer cells, where it...
