by University of Geneva The protein Vav3 (in green) creates «bacterial docking stations» on the surface (in red) of respiratory cells (nuclei in blue) that facilitate airways’ infection in patients with cystic fibrosis. Credit: UNIGE, laboratoire Chanson Cystic fibrosis, one of the most common genetic diseases in Switzerland, causes severe respiratory and digestive disorders. Despite...
by University of Leeds The blood flow in the surface blood vessels of a mouse that was not treated with M-3. Drugs that were developed to treat Alzheimer’s Disease could be re-purposed to prevent—or even reverse—the damage done to the blood vessels in people who are obese or suffer from type 2 diabetes, according to...
The findings provide a clear path to uncovering new drugs to control addiction, pain and neurological disorders such as epilepsy and muscle spasticity CREDIT: (ILLUSTRATION BY YEKATERINA KADYSHEVSKAYA/BRIDGE INSTITUTE AT THE USC MICHELSON CENTER FOR CONVERGENT BIOSCIENCE.) As the body goes about its daily business, molecules called neurotransmitters control the level of electrical activity within...
Precise delivery of therapeutic drugs into diseased tissue remains a challenge in a variety of cases. Tumors can be hard to seed with chemo agents, particularly when the blood flow is not favorable for delivery. Now, researchers at the Max Planck Institute for Intelligent Systems in Germany have developed microscopic drug delivery devices that can...
Children’s Hospital Los Angeles surgeon achieves milestone in using tissue engineering to grow complete gut nervous system CHILDREN’S HOSPITAL LOS ANGELES Babies with Hirschsprung’s disease are born with an incomplete or absent gut nervous system. Children’s Hospital Los Angeles investigator Tracy Grikscheit, MD, runs a laboratory that investigates the therapeutic potential of tissue engineering –...
Scientists from Hong Kong Baptist University (HKBU) have developed a novel technique that can produce pure therapeutic drugs without the associated side effects. The approach, which uses a nanostructure fabrication device, can manipulate the chirality of drug molecules by controlling the direction a substrate is rotated within the device, thus eliminating the possible side effects...
by Jessica Sinclair, University of Ottawa When an actor is unable to perform in the theatre, an understudy—ideally one with some practice in the role—can take her place on stage. A study from Dr. Bernard Jasmin’s laboratory at the University of Ottawa and published today in Nature Communications shows that the same is true of...
UNIVERSITY OF KENTUCKY LEXINGTON, Ky. (Feb. 5, 2020) – A new study by University of Kentucky Markey Cancer Center researchers suggests that targeting a protein known as heat shock protein 47 (Hsp47) could be key for suppressing breast cancer metastasis. Metastasis is when cancer cells spread from the primary tumor to surrounding tissues and distant...
A peptide extracted from the cyanobacterium ‘spirulina’ may contrast high blood pressure by dilating blood vessels ISTITUTO NEUROLOGICO MEDITERRANEO NEUROMED I.R.C.C.S Spirulina is more and more celebrated as a “superfood” because of its possible beneficial properties, albeit its mechanism of action is still subjected to investigation. With the scientific name of Arthrospira platensis, spirulina is...
A multi-institution international team led by researchers at Baylor College of Medicine has developed a new strategy to overcome one of the main obstacles to the treatment of brain cancer—access to the tumor. Under the influence of cancer, the blood-brain barrier diverts immune T cells that attempt to enter the brain to fight the tumor....
