by Thamarasee Jeewandara , Medical Xpress An interactive cellular atlas representing the glomerulus and renal capsule of the kidney. Image downloaded via https://atlas.kpmp.org/explorer/ Credit: Science Advances (2022). DOI: 10.1126/sciadv.abn4965 A team of researchers including Jens Hansen, Rachel Sealfon, Rajastree Menon, and colleagues of the Kidney Precision Medicine Project, built on an existing specific human kidney tissue atlas relevant to...
by UT Southwestern Medical Center A UTSW study finds that cells called pericytes (green), which wrap around the outside of blood vessels, secrete nerve growth factor (NGF) to simulate elongation of nerves into soft tissue injury. That process is associated with abnormal bone growth during healing. Deletion of NGF or its receptor (TrkA) reduces aberrant...
WELLCOME TRUST SANGER INSTITUTE For the first time, scientists are able to study changes in the DNA of any human tissue, following the resolution of long-standing technical challenges by scientists at the Wellcome Sanger Institute. The new method, called nanorate sequencing (NanoSeq), makes it possible to study how genetic changes occur in human tissues with...
Cleveland Clinic researchers publish findings in Science Signaling CLEVELAND CLINIC In a new study published in Science Signaling, Cleveland Clinic researchers have identified a novel target for new therapies that may help to treat or prevent a host of fibrotic conditions, which contribute to nearly half of overall mortality in the United States. Fibrotic diseases...
OCTOBER 31ST, 2019 MEDGADGET EDITORS MEDICINE, NANOMEDICINE While there has been a great deal of work on a variety of micro- and nanoparticles that can deliver drugs and other therapies within the body, compared with bacteria they’re extremely rudimentary in how they can move within the body. Most are simply carried along by the blood...
Posted Today Researchers have discovered that a key cell type involved in liver injury and cancer consists of two cellular families with different origins and functions. The research by academics from the Universities of Edinburgh and Bristol and funded by the Wellcome Trust and Medical Research Council is published in Nature Communications. The distinguishing feature of...
by Research Institute of Molecular Pathology B cells are white blood cells that generate antibodies against an almost unlimited number of pathogens, a capacity that is vital for any higher organism. However, establishing a diverse repertoire of pathogen recognition comes at a price, as some B cells will inevitably go wild and turn against the...
ECOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE Tissue engineers create artificial organs and tissues that can be used to develop and test new drugs, repair damaged tissue and even replace entire organs in the human body. However, current fabrication methods limit their ability to produce free-form shapes and achieve high cell viability. Researchers at the Laboratory of Applied Photonics Devices...
UNIVERSITY OF BIRMINGHAM Pioneering research by scientists at the Universities of Oxford and Birmingham published today [May 29th] in Nature brings us a step closer to developing targeted therapies for inflammatory diseases. The research team shows, for the first time, that different types of fibroblasts – the most common cells of connective tissue in animals – are organised in different layers in...
Abstract The dynamic nature of modern warfare, including threats and injuries faced by soldiers, necessitates the development of countermeasures that address a wide variety of injuries. Tissue engineering has emerged as a field with the potential to provide contemporary solutions. In this review, discussions focus on the applications of stem cells in tissue engineering to...
