by Kerstin Wild, Leibniz Institute for Immunotherapy Wound healing and target killing are both effector mechanisms of CD8 T cells. (A) Combined proliferation and killing assay in the presence of influenza-specific CD8 T cells and varying amounts of pulsed peptides on MRC-5 and HaCaT cells seeded in a 30:70 ratio. Left, representative image with labels...
by Nahia Barberia, Institute for Research in Biomedicine (IRB Barcelona) On the right, cells in the pancreas undergoing reprogramming; on the left, regular pancreas tissue. Credit: IRB BarcelonaVitamin B12 is a well-known micronutrient that has long been acknowledged for its essential role in maintaining nerve function, supporting red blood cell production, and facilitating DNA synthesis,...
by Tokyo Medical and Dental University (Left) Jigsaw-shaped hydrophobic surface is the key structure forming nanofiber through β-sheet assembly. (Right) JigSAP-tagged VEGF (VEGF-JigSAP) is efficiently incorporated into and released from JigSAP hydrogels. Credit: Center for Brain Integration Research, TMDU Recreating native physiological processes in manmade materials imitating the biological structures involved in wound healing has...
Researchers in Japan develop a novel strategy for tissue regeneration, which is a better alternative to conventional tissue regeneration methods TOKYO UNIVERSITY OF SCIENCE Joint diseases, such as knee osteoarthritis, are common in the elderly population and severely impair their quality of life. Conventional treatments like artificial joint replacements offer temporary relief but come with...
Reviewed by James Ives Researchers at the University of Zurich show that different stem cell populations are innervated in distinct ways. Innervation may therefore be crucial for proper tissue regeneration. They also demonstrate that cancer stem cells likewise establish contacts with nerves. Targeting tumor innervation could thus lead to new cancer therapies. Stem cells can...
by University of Zurich Stem cells can generate a variety of specific tissues and are increasingly used for clinical applications such as the replacement of bone or cartilage. However, stem cells are also present in cancerous tissues and are involved in cancer progression and metastasis. Nerves are fundamental for regulating the physiological and regenerative processes...
Researchers at King’s College London have used single cell RNA sequencing to identify a type of cell that may be able to regenerate liver tissue, treating liver failure without the need for transplants. In a paper published today in Nature Communications, the scientists have identified a new type of cell called a hepatobiliary hybrid progenitor (HHyP), that forms during our early development in the womb....
Scientists have found a way of mimicking our body’s natural healing process, using cell derived nano-sized particles called vesicles, to repair damaged tissue. The paper, published in Scientific Reports, describes a new approach to bone regeneration; stimulating cells to produce vesicles which can then be delivered to facilitate tissue regeneration. The research team, led by the University of Birmingham,...
Cell (stock image). The use of iPSCs to generate tissues would revolutionize transplantation, facilitating the growth of artificial organs, say authors. Houston Methodist researchers have identified an immune pathway that promotes the formation of a cell that can develop into new tissues and organs. In a new study published in the journal Stem Cells, a team...
