Tag: <span>TLR4 Knockout</span>

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Reducing Systemic Inflammation via TLR4 Knockout
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Reducing Systemic Inflammation via TLR4 Knockout

TLR4 is one of a number of cell surface receptors that mediate innate immune cell reactions to molecules indicative of damage in the body. Some fraction of the chronic inflammation of aging is caused by increases in damage-associated molecular patterns that trigger receptors of this nature, and consequent maladaptive reactions on the part of the innate immune system. Does it help to block this...