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Tool Uses Genetics to Diagnose Early Inflammatory Arthritis

Lucy Hicks A new diagnostic tool can effectively discriminate different rheumatologic conditions and could potentially aid in the diagnosis of early inflammatory arthritis. The algorithm — called Genetic Probability tool (G-PROB) — uses genetic information to calculate the probability of certain diseases. “At such an early stage of disease, it’s not always easy to determine...

Study gives digital prostate exams the finger as cancer screening tool
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Study gives digital prostate exams the finger as cancer screening tool

By Paul McClure A study has found that digital prostate exams are not as effective at detecting cancer as thoughtOriginal image from Depositphotos new study has found that digital rectal examination alone or in combination with a blood test does not improve prostate cancer detection compared to the blood test alone. The findings suggest that digital...

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Tool targets cancer-causing fusions’ weak spot

by St. Jude Children’s Research Hospital Model of fusion etiology and study design. a Theoretical mechanisms of oncogenic fusion formation. Scenario 1: the DNA breakpoints (red lines) can lead to the fusion of coding exons (thick boxes) from N’ gene to 5’ untranslated region (UTR; thin boxes) of C’ gene and result in the conversion of the...

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New open-source single-cell analysis tool

Researchers at Penn and colleagues have developed a tool to analyze single cells that assesses both the patterns of gene activation within a cell and which sibling cells shared a common progenitor. Recent advances in analyzing data at the single-cell level have helped biologists uncover new information about cells and their behaviors. One commonly used approach, known...

Tool to spot breast cancer at home wins UK Dyson award
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Tool to spot breast cancer at home wins UK Dyson award

7 September 2022 IMAGE SOURCE, JAMES DYSON AWARD By Shiona McCallumTechnology reporter A device to help detect breast cancer has won the prestigious UK James Dyson Award. The Dotplot aims to help women self-check at home and track any changes they may find on an app. Breast cancer is the second most common cause of...

Epidemiologists develop state-of-the-art tool for measuring the pace of aging
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Epidemiologists develop state-of-the-art tool for measuring the pace of aging

JANUARY 18, 2022 by  Columbia University’s Mailman School of Public Health Credit: Pixabay/CC0 Public Domain Researchers at Columbia University Mailman School of Public Health have developed a new blood test to measure the pace of biological aging. Based on an analysis of chemical tags on the DNA contained in white blood cells, called DNA methylation marks,...

A tool for more inclusive autism screening
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A tool for more inclusive autism screening

by  University of Pennsylvania Figure 1. Sample DCI Item. Credit: Harris et al., Pediatrics, 2021. Screening tools for autism spectrum disorder (ASD) often fail to identify ASD among children from low-income families and racial/ethnic minority groups, particularly when English is not the family’s primary language. A new visually-based tool may reduce these disparities at a pivotal point...