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Toxin provides clues to long-term effects of diarrhea caused by E. coli
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Toxin provides clues to long-term effects of diarrhea caused by E. coli

by Tamara Bhandari,  Washington University School of Medicine Toxin-producing E. coli bacteria (green) attach to human intestinal cells expressing the protein CEACAM6 (red). A study from researchers at Washington University School of Medicine in St. Louis has found that a toxin produced by E. coli changes intestinal cells to benefit itself, an ability that could provide a clue...

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Parkinson’s: Study reveals how cancer drug reduces toxic protein in brain

By Catharine Paddock PhD Fact checked by Paula Field Laboratory and animal studies have suggested that the leukemia drug nilotinib could alleviate symptoms of Parkinson’s disease. Now, using early results from a clinical trial in humans, scientists have worked out how the drug reduces toxic protein and raises dopamine levels in the brain. Loss of dopamine,...

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New insights into the toxin behind tetanus

Tetanus toxin is the neurotoxin that causes lockjaw. Many are vaccinated, but tetanus still kills tens of thousands of people per year worldwide. Researchers from the Department of Biochemistry and Biophysics, led by Dr. Pål Stenmark, have now uncovered the poison’s structure. For the first time, the way the poison is constructed has been revealed....