by Li Yuan, Chinese Academy of Sciences Distinct chemokines selectively induce HIV-1 gp120-integrin α4β7 binding via triggering conformer-specific activation of α4β7. a Adhesion of CD4‒ Jurkat T cells or CD4‒α4β7+ Jurkat T cells to immobilized gp120 in 1 mM Ca2+/Mg2+ or 0.5 mM Mn2+. b A diagram of the V1 and V2 domains of gp120 was drawn based...
