by Kyoto University Credit: Stem Cells Translational Medicine (2024). DOI: 10.1093/stcltm/szae066 Researchers have developed a technique to enhance the effectiveness of cell transplantation therapy for stroke or traumatic brain injury. The team, including Professor Jun Takahashi, Researcher Bumpei Samata, and Graduate Student Keitaro Yamagami from the Department of Clinical Application at CiRA, published their study in the journal Stem Cells Translational...
Tag: <span>traumatic brain injury</span>
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Study: Traumatic brain injury leads to widespread changes in neural connections
by Tufts University Credit: Pixabay/CC0 Public DomainA head injury serious enough to affect brain function, such as that caused by a car accident or sudden fall, leads to changes in the brain beyond the site of impact, Tufts University School of Medicine scientists report in the journal Cerebral Cortex. In an animal model of traumatic brain...
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Improving functional recovery of the brain and heart after traumatic brain injury
by Kathryn Ryan, Mary Ann Liebert, Inc Credit: CC0 Public DomainA new study in the Journal of Neurotrauma has shown that Angiotensin II type 2 receptor (AT2R) activation improves neurological and cardiac deficiencies caused by traumatic brain injury (TBI) in mice. AT2R activation is known to exert protective roles in the brain and heart. TBI of...
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Cells wearing ‘backpacks’ shrink traumatic brain injury lesions by 56%
By Paul McClure Researchers have fitted “backpacks” to inflammatory cells to treat traumatic brain injury DepositphotosBy fitting microparticle ‘backpacks’ to important inflammatory cells called macrophages, researchers significantly reduced lesion size and inflammation caused by traumatic brain injury. Working with biology rather than against it, this novel approach has the potential to be an effective treatment for...
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Pain is a major problem for individuals with traumatic brain injury, researchers say
by Wolters Kluwer Health Credit: Pixabay/CC0 Public DomainChronic pain affects approximately 60% of people living with traumatic brain injury (TBI), even up to 30 years after injury, according to new research published in the Journal of Head Trauma Rehabilitation. “This is the first study to examine the experience of chronic pain in a large TBI sample...
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Trends in suicide rates among post-9/11 veterans with and without traumatic brain injury
JAMA NETWORK About The Study: In a large cohort of U.S. military veterans serving after 9/11, suicide rates increased more than 10-fold from 2006-2020, a significantly greater rate of change than in the U.S. adult population. Over the 15-year period, veterans with traumatic brain injury (TBI) had suicide rates 56% higher than veterans without TBI...
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Why depression after traumatic brain injury is distinct — and less likely to respond to standard treatment
By Elizabeth Cooney July 6, 2023 ADOBE Traumatic brain injury multiplies the risk of major depression eightfold. While the emotional trauma of whatever caused such deep damage may be understandable, from a blast in a war zone to a blow on the playing field, there’s a physiological component, too, that neuroscientists have long suspected but have...
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Is service-related traumatic brain injury in veterans a prelude to Alzheimer’s disease?
MARY ANN LIEBERT, INC./GENETIC ENGINEERING NEWS IMAGE: FOCUSES ON THE LATEST ADVANCES IN THE CLINICAL AND LABORATORY INVESTIGATION OF TRAUMATIC BRAIN AND SPINAL CORD INJURY. EMPHASIS IS ON THE BASIC PATHOBIOLOGY OF INJURY TO THE NERVOUS SYSTEM, AND THE PAPERS AND REVIEWS EVALUATE PRECLINICAL AND CLINICAL TRIALS TARGETED AT IMPROVING THE EARLY MANAGEMENT AND LONG-TERM...
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Biomaterial can be injected intravenously and has potential application in heart attacks, traumatic brain injury
by Ioana Patringenaru, University of California – San Diego The biomaterial is based on a hydrogel developed at UC San Diego. Credit: David Baillot/University of California San Diego A new biomaterial, which can be injected intravenously, reduces inflammation in tissue and promotes cell and tissue repair. The biomaterial was tested and proven effective in treating...
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Updated guidelines on cognitive rehabilitation after traumatic brain injury
WOLTERS KLUWER HEALTH January 3, 2023 – A rapidly growing body of evidence shows the importance and effectiveness of cognitive rehabilitation for individuals with traumatic brain injury (TBI). A major update of the groundbreaking INCOG guidelines for cognitive rehabilitation following TBI is presented in the January/February special issue of the Journal of Head Trauma Rehabilitation (JHTR). The official journal of...