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Traumatic brain injury ‘remains major global health problem’ say experts
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Traumatic brain injury ‘remains major global health problem’ say experts

by University of Cambridge Credit: Pixabay/CC0 Public Domain A new report highlights the advances and challenges in prevention, clinical care, and research in traumatic brain injury, a leading cause of injury-related death and disability worldwide. The report, by the 2022 Lancet Neurology Commission, has been produced by world-leading experts, including co-lead author Professor David Menon...

Early blood tests predict death, severe disability for traumatic brain injury
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Early blood tests predict death, severe disability for traumatic brain injury

MICHIGAN MEDICINE – UNIVERSITY OF MICHIGAN IMAGE: A GRAPHIC OF TBI WITH BLOOD TEST VIALS. CREDIT: JUSTINE ROSS, MICHIGAN MEDICINE A study finds that blood tests taken the day of a traumatic brain injury can predict which patients are likely to die or survive with severe disability, allowing clinicians to make decisions earlier on possible...

Neuroscientists create maps of the brain after traumatic brain injury
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Neuroscientists create maps of the brain after traumatic brain injury

by University of California, Irvine Co-first author and Anatomy & Neurobiology graduate student, Alexa Tierno, holds a mouse brain made transparent to visualize connections between nerve cells in the entire brain. An image of neurons in medial entorhinal cortex projecting to transplanted interneurons in damaged hippocampus is shown in the background. Credit: UCI School of...

Symptom persistence during first year following traumatic brain injury
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Symptom persistence during first year following traumatic brain injury

by Mary Ann Liebert, Inc Number of symptoms endorsed at any severity by traumatic brain injury (TBI) severity subgroup and time. mTBI, mild TBI (admission Glasgow Coma Scale score 13–15); msTBI, moderate or severe TBI (admission Glasgow Coma Scale score 3–12). Credit: Journal of Neurotrauma (2022). DOI: 10.1089/neu.2021.0348 More than 70% of patients with traumatic brain injury...

Early diagnostic and prognostic biomarkers of traumatic brain injury
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Early diagnostic and prognostic biomarkers of traumatic brain injury

by  University of Eastern Finland Credit: Unsplash/CC0 Public Domain Acute elevation in certain plasma microRNAs (miRNAs), along with downregulation of the clusterin protein within two days post-injury can act as early diagnostic and prognostic biomarkers for traumatic brain injury, according to the doctoral dissertation of Shalini Das Gupta, MSc. Traumatic brain injury (TBI) occurs when an...

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Scientists identify mechanism linking traumatic brain injury to neurodegenerative disease

ELIFE  Scientists have revealed a potential mechanism for how traumatic brain injury leads to neurodegenerative diseases, according to a study in fruit flies, and rat and human brain tissue, published today in eLife. The results could aid the development of treatments that halt the progression of cell damage after brain injury, which can otherwise lead to...

Implantable Hydrogel Helps Neurons Recover After Traumatic Brain Injury
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Implantable Hydrogel Helps Neurons Recover After Traumatic Brain Injury

APRIL 30TH, 2021   MEDGADGET Traumatic brain injuries (TBI) often lead to cognitive disabilities and permanent neural tissue damage, for which effective therapies do not exist. The serious cognitive impairments that patients experience and the burden on caretakers can be enormous, necessitating a constant search for treatments that may help. Researchers at University of Georgia have now...

Brain changes following traumatic brain injury share similarities with Alzheimer’s disease
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Brain changes following traumatic brain injury share similarities with Alzheimer’s disease

by Jenesse Miller,  University of Southern California The image displays a TBI-affected brain’s white matter connectivity as inferred using diffusion tensor imaging and streamline tractography. The brain surface is rendered as a translucent layer to provide anatomical context for the streamline display. White matter connections and the brain surface are displayed using different colors across for...

Light therapy helps veterans treated for traumatic brain injury
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Light therapy helps veterans treated for traumatic brain injury

by  American Physiological Society Credit: CC0 Public Domain A new study by researchers at the VA Portland Health Care System in Oregon found that augmenting traditional treatment for traumatic brain injury (TBI) with morning bright light therapy (MBLT) improved physical and mental symptoms for participants. The team will present their work virtually at the American Physiological Society’s (APS)...

Complement inhibition reverses mental losses in preclinical traumatic brain injury models
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Complement inhibition reverses mental losses in preclinical traumatic brain injury models

by  Medical University of South Carolina Hippocampal slices of an uninjured brain (top) or a brain three months after TBI (bottom). There is an increase in astrocytes (green) following a brain injury. Credit: Dr. Stephen Tomlinson of the Medical College of Wisconsin. Traumatic brain injury (TBI) is a major cause of disability and a risk factor...