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New drug target to treat pain from visceral organs
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New drug target to treat pain from visceral organs

by Thomas Jefferson University Graphical abstract. Credit: Journal of Clinical Investigation (2022). DOI: 10.1172/JCI165578 An approved drug for chronic constipation also relieves the pain associated with that condition. New research by Scott Waldman, MD, Ph.D., chair of pharmacology, physiology and cancer biology at Jefferson, demonstrates that the drug’s two actions can be separated biologically—a finding that may offer ways...

New drugs with high abuse potential more likely to be approved, go to market to treat pain
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New drugs with high abuse potential more likely to be approved, go to market to treat pain

by American Society of Anesthesiologists  Credit: CC0 Public Domain “Despite the prevalence and societal costs of pain in the United States, investment in pain medication development is low, due in part to poor understanding of the probability of successful development of such medications,” said the authors of a study published online first in Anesthesiology. “The opioid...