by KU Leuven Figure 1. Interrogation of the tumor derived bulk-RNAseq or tumor/blood single-cell (sc)-RNAseq data of patients with cancer. (A,B) The t-distributed stochastic neighbor embedding (tSNE) visualizations of indicated immune cell types, from scRNAseq data from patients with renal cell and large cell neuroendocrine carcinoma (n=4 patients in total) (derived from GSE139555) isolated from tumor...
by Rhoda Madson, Mayo Clinic Credit: Mayo Clinic November is Gastric Cancer Awareness Month. Gastric cancer, also known as stomach cancer, was the sixth most common cancer in 2020, with 1.09 million new cases, according to the World Health Organization. It was the fifth most common cause of cancer death in 2020. Gastric cancer is common...
By Michelle Rostamian CARMEN JIMÉNEZ / EYEEM VIA GETTY IMAGESFungal acne spots are generally small and all the same size, while bacterial acne can be varying sizes and also show up as blackheads, nodules, and cysts. For many people, any deviation from clear skin means it’s time for a treatment plan, especially when it comes...
by Bill Snyder, Vanderbilt University Medical Center Credit: CC0 Public Domain Analogs of signaling molecules called EETs may improve treatment of insulin resistance, a primary risk factor for development of Type 2 diabetes and cardiovascular disease, according to a new paper by researchers at Vanderbilt University Medical Center. Ambra Pozzi, Ph.D., and colleagues previously reported that EETs...
by Delthia Ricks, Medical Xpress PET scan of a human brain with Alzheimer’s disease. Credit: public domain Two drugs approved decades ago not only counteract brain damage caused by Alzheimer’s disease in animal models, the same therapeutic combination may also improve cognition. Sounds like a slam dunk in terms of a cure—but not yet. Researchers...
by Jasmine Lee, Cold Spring Harbor Laboratory Credit: Unsplash/CC0 Public Domain Inositol is a sugar required for cells to survive. Most cells either get it from the bloodstream or make it themselves. Since there is plenty of inositol available, some cancer cells decide to stop making it. Cold Spring Harbor Laboratory Professor Christopher Vakoc and...
INSTITUTE FOR RESEARCH IN BIOMEDICINE (IRB BARCELONA) IMAGE: MUTATIONS CORRELATED WITH MECHANISMS OF RESISTANCE TO TREATMENT (IRB BARCELONA) CREDIT: IRB BARCELONA Barcelona, 25 October 2021- It is estimated that 80% of women will suffer from vaginal candidiasis at least once in their lives. In addition to superficial infections, which can be oral or vaginal and...
by University of Kent Credit: Pixabay/CC0 Public Domain New research has revealed the differences in mechanism behind cancer’s resistance to the major class of anti-cancer drugs known as nucleoside analogs. Nucleosides are molecules containing the genomic information that can be chemically modified into so-called nucleoside analogs to cause them to inhibit DNA formation in cancer cells, causing the...
by Hackensack Meridian Health Credit: Pixabay/CC0 Public Domain Scientists from the Hackensack Meridian Center for Discovery and Innovation, working with collaborators from across the globe, uncovered the mechanism of action of a novel anti-tuberculosis drug that they have helped develop. The new findings show how the enzyme inhibitor triaza-coumarin, or TA-C, is metabolized by the...
by City of Hope National Medical Center Mammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public Domain City of Hope, a world-renowned cancer research and treatment center, has identified how cancer cells in patients with early-stage breast cancer change and become resistant to hormone or combination therapies, according to a new study published...
