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A safer cell therapy harnesses patient T cells to fight multiple myeloma

AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE A treatment for multiple myeloma that harnesses the body’s cancer-fighting T cells was safe in humans and showed preliminary signs of effectiveness, according to a clinical trial involving 23 patients with relapsed or treatment-resistant disease. Although more research is needed to determine how well the treatment works, the...

New clues to lung-scarring disease may aid treatment
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New clues to lung-scarring disease may aid treatment

by Vanderbilt University Medical Center Scientists at Vanderbilt University Medical Center (VUMC) and the Translational Genomics Research Institute (TGen) in Phoenix, Arizona, have discovered previously unreported genetic and cellular changes that occur in the lungs of people with pulmonary fibrosis (PF). Their findings, reported Wednesday, July 8, in the journal Science Advances, should aid the...

Oncologists, patients weigh treatment and coronavirus risk: ‘Cancer is a disease that does not wait.’
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Oncologists, patients weigh treatment and coronavirus risk: ‘Cancer is a disease that does not wait.’

by Kate Thayer, Chicago Tribune As the coronavirus pandemic intensified, so did Catherine Payne’s strategies for avoiding infection while undergoing chemotherapy. The 33-year-old Chicago woman was diagnosed with stage 3 breast cancer in November and began treatment soon after, suppressing her immune system. What started as avoiding the gym, air travel and limiting contact with...

A potential treatment for life-threatening neurological diseases
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A potential treatment for life-threatening neurological diseases

by University of Barcelona A group of life-threatening neurological conditions affecting children has been linked to an antibody that points to potential treatment, according to an observational multicenter study involving 535 children with central nervous system (CNS) demyelinating disorders and encephalitis, published in The Lancet Neurology journal. The findings suggest that the myelin oligodendrocyte glycoprotein...

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Diagnosis and Treatment of Adults With Community-Acquired Pneumonia

Gregory Olson, MD1; Andrew M. Davis, MD, MPH2 Author Affiliations Article Information JAMA. Published online February 6, 2020. doi:10.1001/jama.2019.21118 Guideline title Diagnosis and Treatment of Adults With Community-Acquired Pneumonia Developers American Thoracic Society (ATS); Infectious Diseases Society of America (IDSA) Release date October 1, 2019 Prior version 2007 Funding source ATS/IDSA Target population Adults with...

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Blood test could lead to cystic fibrosis treatment tailored to each patient

Researchers at Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago, and colleagues, used a blood test and microarray technology to identify distinct molecular signatures in children with cystic fibrosis. These patterns of gene expression ultimately could help predict disease severity and treatment response, and lead to therapies tailored to each patient‘s precise biology. Findings were published in Physiological Genomics. “Our findings pave the way...