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Study shows early success of a novel drug in treating a rare and chronic blood cancer
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Study shows early success of a novel drug in treating a rare and chronic blood cancer

by The Mount Sinai Hospital blood donationCredit: Pixabay/CC0 Public DomainA novel treatment for polycythemia vera, a potentially fatal blood cancer, demonstrated the ability to control overproduction of red blood cells, the hallmark of this malignancy and many of its debilitating symptoms in a multi-center clinical trial led by the Icahn School of Medicine at Mount...

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NextGen Precision Health researchers uncover potential treatment for cardiovascular complications from type 2 diabetes

Two new studies originating from the Roy Blunt NextGen Precision Health building provide promise for diabeticsPeer-Reviewed Publication UNIVERSITY OF MISSOURI-COLUMBIA New research at the Roy Blunt NextGen Precision Health building has discovered a potential treatment for an underlying cause of cardiovascular disease in people with Type 2 diabetes. More than 30 million Americans live with...

New insight into old IBD drug could improve treatments
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New insight into old IBD drug could improve treatments

by Jim Schnabel, Cornell University Graphical Abstract. Credit: Cell Reports Medicine (2024). DOI: 10.1016/j.xcrm.2024.101431Although it is one of the oldest medications used to treat patients with inflammatory bowel disease (IBD) and an effective treatment for an associated arthritis condition called spondyloarthritis (SpA), sulfasalazine’s mechanism of action has been unclear. Now, researchers at the Jill Roberts Center...

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Treating liver cancer with microrobots

The idea of injecting microscopic robots into the bloodstream to heal the human body is not new. It’s also not science fiction. Guided by an external magnetic field, miniature biocompatible robots, made of magnetizable iron oxide nanoparticles, can theoretically provide medical treatment in a very targeted manner. Until now, there has been a technical obstacle:...

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Mapping potential pathways to motor neuron disease treatment

by Queensland Brain Institute Cells expressing a mutant protein, TDP-43, involved in MND pathology. Credit: Dr Rebecca San Gil at the Queensland Brain InstituteFor the first time, researchers from the University of Queensland (UQ) have mapped out the proteins implicated in the early stages of motor neuron disease (MND). Dr. Rebecca San Gil from Associate...

With regular exercise, medical weight loss treatment does not have to be permanent
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With regular exercise, medical weight loss treatment does not have to be permanent

by University of Copenhagen Credit: Unsplash/CC0 Public DomainFor nearly a year, we have been debating weight loss drugs like Wegovy, Zepbound, Saxenda and similar products and what happens when people stop taking them. Are they able to maintain weight loss? A new Danish study sheds light on the matter. You have probably noticed that weight loss...

Can Ozempic treat depression? Early signs point to yes
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Can Ozempic treat depression? Early signs point to yes

by Lisa Jarvis, Bloomberg Opinion Credit: Unsplash/CC0 Public DomainAdd depression to the growing list of chronic diseases that obesity medicines might alleviate. Signs of improved mental health are showing up in the health records of people who take the broader class of medicines known as GLP-1s, which include Novo Nordisk’s Wegovy and Eli Lilly &...

Why leukemic stem cells not harmed by chemotherapy begin to grow and produce AML cells after treatment
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Why leukemic stem cells not harmed by chemotherapy begin to grow and produce AML cells after treatment

by University of Birmingham AML-subtype specific gene expression and chromatin accessibility is established in LSCs. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-45691-4The mystery of why myeloid leukemia starts to grow again after chemotherapy has killed the bulk of malignant cells, and how growth may be blocked by repurposed drugs, has potentially been solved through new research. The...

How to recognize and treat a pinched nerve in the neck
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How to recognize and treat a pinched nerve in the neck

Symptoms of a pinched nerve in the neck can include neck pain, hand and arm numbness, and shoulder weakness. Treatments like physical therapy and immobilizing the neck can help ease pain and relieve pressure on the nerve. A pinched nerve occurs when a nerve becomes irritated or compressed. The medical term for when this happens...

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An anticancer drug opens a new path for the treatment of Parkinson’s

The metabolic product of an anticancer drug demonstrates potential activity in neurons derived from Parkinson’s patients and a synergistic action, together with the original drug, in prostate cancer cellsPeer-Reviewed Publication SPANISH NATIONAL RESEARCH COUNCIL (CSIC) L’Hospitalet de Llobregat, February 8th, 2024. Once they enter the body, drugs, apart from carrying out their therapeutic function, are...