by Deb Balzer, Mayo Clinic News Network Credit: Miriam Alonso from Pexels Dupuytren (DOO-puh-tren) contracture is a disorder that can cause the fingers to curl in, primarily the ring and small fingers. It’s a genetic condition mostly affecting men over 60 of Northern European descent. Others at risk include people with diabetes and those with...
by Lori Solomon The U.S. Food and Drug Administration has approved Takeda Pharmaceuticals Adzynma, the first recombinant protein product indicated for prophylactic or on-demand enzyme replacement therapy (ERT) in adult and pediatric patients with congenital thrombotic thrombocytopenic purpura (cTTP). Adzynma is a purified recombinant form of the ADAMTS13 enzyme that enhances the low levels of...
More accurate detection of a specific molecular marker in leukemic cells will help assess measurable residual disease and guide treatment decisions, improving patient outcomes, report investigators in The Journal of Molecular DiagnosticsPeer-Reviewed Publication ELSEVIER Philadelphia, November 13, 2023 – A novel assay that detects a unique molecular marker in patients with acute myeloid leukemia (AML)...
by Virginia Commonwealth University Axial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domain Preclinical research published in the Journal for ImmunoTherapy of Cancer points to a promising new treatment option for people with pancreatic cancer. Researchers from VCU Massey Comprehensive Cancer Center and the VCU Institute of Molecular Medicine (VIMM)...
An international team of researchers has demonstrated that genetically engineered yeast cells can produce the natural plant product alstonine, which has shown positive effects in treating schizophrenia.Peer-Reviewed Publication TECHNICAL UNIVERSITY OF DENMARK THE RESEARCH TEAM BEHIND EXPERIMENTS WITH GENETICALLY ENGINEERED YEAST CELLS. FROM LEFT: JIE ZHANG (CO-FOUNDER & CSO BIOMIA), BEATA LEHKA (POSTDOC, DTU BIOSUSTAIN),...
by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE) Credit: Cell (2023). DOI: 10.1016/j.cell.2023.10.001 Researchers at DZNE and Charité–Universitätsmedizin Berlin have pioneered a novel treatment for the most common autoimmune encephalitis. By reprogramming white blood cells to target and eliminate disease-causing cells, the approach offers a new level of precision and efficiency. The technique...
by Chinese Academy of Sciences Retrograde AAV selectively targets D1-MSNs and rescues parkinsonian symptoms with chemogenetic modulation. Credit: SIAT Researchers from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences (CAS) and their collaborators have developed a gene therapy strategy to selectively manipulate Parkinson’s disease-affected circuitry and attenuate the core motor symptoms...
by Oxford University Press Credit: Unsplash/CC0 Public Domain According to a new paper in Rheumatology, published by Oxford University Press, JAK inhibitors, which doctors have used to treat patients with arthritis despite concerns about the effectiveness of such drugs, actually do work quite well. In a multicenter, retrospective study Japanese researchers found that the drugs resulted...
Sanjai Sinha, MDWritten by Kim Grundy, PT | Reviewed by Sanjai Sinha, MD Key takeaways: If you’ve ever felt a hard, painful spot on your neck or shoulders after sitting at your desk all day, you probably had a muscle knot. These sensitive spots can cause muscle aches and limit your range of motion. And...
by University College London Credit: samer daboul from PexelsA new drug candidate, based on pioneering UCL and Moorfields Eye Hospital research and currently under development by SIFI S.p.A., has been found to be highly effective in treating a rare sight-threatening eye infection in a new international clinical trial. The findings, published in Ophthalmology, describe the efficacy...
