by deCODE genetics Credit: Pixabay/CC0 Public DomainA large international study led by deCODE Genetics on the genetics of migraine provides novel insights into the biology of migraine enabling detection of rare variants protecting against migraine, opening an avenue for potential development of novel drug targets. In a study published in Nature Genetics a group of...
by Northwestern University Graphical abstract. Credit: Journal of Clinical Investigation (2023). DOI: 10.1172/JCI161142A new study has revealed that Metixene, an antiparkinsonian drug, has shown remarkable potential as a novel treatment for metastatic breast cancer and brain metastases, providing hope for patients facing this devastating disease. The study was conducted by a team of researchers led by...
by Louisiana State University CB-103 shows synergy with paclitaxel and fulvestrant in breast cancer cell lines. TNBC (HCC1187) and ER+ BC (MCF-7) cells were treated with combinations of CB-103 (150 nM–10 μM) with paclitaxel or fulvestrant (75 nM–20 μM) and cell viability was measured after 72 h of treatment. Synergy between CB-103 and paclitaxel or fulvestrant...
WEILL CORNELL MEDICINE A non-opioid designer molecule for treating chronic neuropathic pain by calming hyperactive pain-sensing neurons in the peripheral nervous system has had promising results in a preclinical study conducted by researchers at Weill Cornell Medicine and the Burke Neurological Institute. In the study, published Aug. 2 in the British Journal of Anaesthesia, the first-in-class drug conceptualized...
This experimental therapy, called NRTX-1001, has the potential to offer drug-resistant temporal lobe epilepsy patients a non-destructive cure for their seizures. The injected cells, derived from human stem cells, are aimed at restoring brain balance and calming seizures. Early results show a more than 90% reduction in seizure frequency in initial patients post-treatment. Key Facts:...
Jul 12, 2023 Mass General Cancer Center’s precision medicine approach resulted in 91 percent reduction in tumor size, with all 15 patients who received one or more cycles of therapy responding to treatment Papillary craniopharyngiomas (PCPs) are a rare type of brain tumor that cause substantial morbidity for patients. While surgery and radiation are often...
UNIVERSITY OF GRONINGEN IMAGE: THIS IS DR. ADÉLA MELCROVÁ, BIOPHYSICIST AT THE UNIVERSITY OF GRONINGEN (THE NETHERLANDS) AND FIRST AUTHOR OF THE PAPER IN NATURE COMMUNICATIONS WHICH SHOWS THAT THE ANTIBIOTIC AMC-109 AFFECTS THE CELL MEMBRANE OF BACTERIA BY DISORDERING ITS ORGANIZATION. THIS IS A NEW WORKING MECHANISM. CREDIT: JOSEF MELCR, UNIVERSITY OF GRONINGEN The...
KADE HAN, LMH HEALTH photo by: Shutterstock When the layer of cells that lines the inside of the uterus grows in areas it’s not supposed to, it causes a painful chronic condition known as endometriosis. It affects about one in 10 women, according to the American College of Obstetricians and Gynecologists, and it’s a common cause...
by Miriam Jones Bradley, RN You’re feeling bloated, nauseous and in pain. What is wrong? It may be gastritis, an inflammation of the stomach lining that can come on suddenly or gradually. It can also lead to other problems, according to the Cleveland Clinic. Here, experts explore gastritis, its causes, risk factors, symptoms, types and treatments, including dietary changes...
Written by Alina Goldenberg, MD, MAS, FAAD | Reviewed by Mandy Armitage, MD Published on March 24, 2022 Key takeaways: Hair loss is common in both men and women. Hair loss can be a sign of an underlying medical issue, so it’s important to see your primary care provider or a dermatologist for help. Treatments...
