by LAURA UNGAR and FREIDA FRISARO Dr. Alfonso Sabater, checks Antonio Vento Carvajal’s eye under a blue light after applying a stain to check to see if more ulcers had developed, before a gene therapy treatment, Thursday, July 6, 2023, at University of Miami Health System’s Bascom Palmer Eye Institute in Miami. Antonio was born...
by University of Queensland TDP-43 pathology causes early activation of the ISR and apoptosis signaling in rNLS8 mice. A Summary of gene expression changes in the cortex of rNLS8 mice over time. B Mechanism schema. TDP-43 mislocalisation induces early activation of multiple cell stress signaling pathways in the cortex of rNLS8 mice even before disease onset, such...
by University of Florida A model shows how glycine molecules (teal) interact with brain cell receptors called GPR158 to influence the nervous system. The dotted lines show hydrogen bonds and weak electrical field attractions that start the signal. Credit: Martemyanov lab at The Wertheim UF Scripps Institute. A common amino acid, glycine, can deliver a...
by Murdoch University Manhattan plot on the association of metabolites detected by mass spectrometry with AD-related SNPs. Features associated with ABCA7 SNPs are annotated. For some metabolites, more than one metabolic feature was found to be associated with AD-related SNPs, and the No. of metabolic features corresponding to the same metabolites is described in brackets....
UNIVERSITY OF ILLINOIS COLLEGE OF AGRICULTURAL, CONSUMER AND ENVIRONMENTAL SCIENCES IMAGE: UNIVERSITY OF ILLINOIS AND MIE UNIVERSITY RESEARCHERS HAVE DETERMINED THE MICROBIAL TOXIN RESPONSIBLE FOR LUNG CELL DEATH IN IDIOPATHIC PULMONARY FIBROSIS AND ACUTE RESPIRATORY DISEASE SYNDROME, AND HAVE DEVELOPED SAFE BLOOD TESTS AND MONOCLONAL ANTIBODY TREATMENTS TO HALT PROGRESSION OF THE DISEASES IN MICE....
The findings could one day lead to individualized treatments aimed at easing their pain. David Beversdorf, a clinician at the University of Missouri Thompson Center for Autism and Neurodevelopmental Disorders, helps patients with autism spectrum disorder (ASD), many of whom may also be struggling with gastrointestinal or digestive issues, including constipation and diarrhea. Children with ASD...
by Worldwide Cancer Research Dr Angus Cameron & Dr Shinelle Menzes at Barts Cancer Institute. Credit: Please credit: Worldwide Cancer Research Researchers at Barts Cancer Institute at Queen Mary University of London, supported by a partnership between the UK charities Worldwide Cancer Research and Pancreatic Cancer Research Fund, have made a discovery that reveals new...
by Case Western Reserve University PET scan of a human brain with Alzheimer’s disease. Credit: public domain An international team led by Case Western Reserve University’s School of Medicine has made a significant breakthrough in understanding why Alzheimer’s disease progresses so rapidly in some people that they die within three years. The researchers found a...
Having stiff fingers can be troubling, as can any loss of mobility. Although arthritis is a key cause of finger stiffness, there are other factors to consider. A doctor will want to thoroughly explore what is causing the issue before recommending treatment. A person may experience stiff fingers at a specific time of the day,...
by Mark Toshner, The Conversation Around 200 symptoms are associated with long COVID. Credit: Pordee Aomboon/Shutterstock The pace of acute therapy and vaccine development for COVID have been dizzying. But even as we hope a route to bringing the pandemic under control is within sight, we’re now facing the possibility of another urgent public health emergency...
