by Liz Ahlberg Touchstone, University of Illinois at Urbana-Champaign The team uses an inverted fluorescence microscope to image cancer cells that are targeted using different light spectra to initiate inflammatory cell death. The process could help create immunotherapy techniques for disease intervention. Credit: Fred Zwicky, University of Illinois at Urbana-ChampaignA new method of precisely targeting...
Tag: <span>triggers</span>
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Feeling hot triggers impulsive behavior and irritability
by Becky Kramer, Washington State University Credit: Pixabay/CC0 Public Domain Heat blanketed Chicago during the summer of 2022, with hot, sticky days followed by sweltering nights. In the nation’s third-largest metro area, about 400 residents tracked their moods during a summer when temperatures hit 100° by mid-June. Were they feeling cranky? Acting impulsively? Lashing out...
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Finding the triggers of inflammation
by Hudson Institute of Medical Research TLR-induced inflammasome priming triggers IL-1β and NLRP3 ubiquitylation. a BMDMs were primed with Lipopolysaccharide (LPS, 50 ng/ml) for up to 8 h (hr) and ubiquitylated (Ub.) proteins were isolated from cell lysates by Tandem Ubiquitin Binding Entity (TUBE) purification. Immunoblots were performed on cell lysates (input) and purified ubiquitylated proteins (TUBEs) for the...