Tag: <span>TRIM28</span>

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TRIM28 Inhibits Alternative Lengthening of Telomeres
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TRIM28 Inhibits Alternative Lengthening of Telomeres

Telomeres are caps of repeated DNA sequences at the ends of chromosomes. A little of the telomere length is lost with each cell division. A somatic cell with short telomeres ceases replication, and usually self-destructs. All cancers must thus continually lengthen telomeres in order to engage in unfettered replication and growth. This makes interference in telomere lengthening an attractive strategy as the basis for...