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Methylation of tRNA-derived fragments regulates gene-silencing activity in bladder cancer
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Methylation of tRNA-derived fragments regulates gene-silencing activity in bladder cancer

by By Jeff Hansen, University of Alabama at Birmingham Systematic mapping of m1A sites in small RNA space. a) Chemical structure of m1A (N1-methyladenosine). b) Overall m1A mapping strategy for small RNAs by combining m1A RIP and m1A-induced mismatch analysis. Synthetic m1A RNA is included as a positive control. c) TGIRT identified as the optimal...