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Could Nixing a Tryptophan Metabolite Temper Alzheimer’s?
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Could Nixing a Tryptophan Metabolite Temper Alzheimer’s?

06 Sep 2024 Could one tiny little amino acid derivative make Alzheimer’s disease a whole lot worse? In the August 25 Science, researchers led by Katrin Andreasson, Stanford University School of Medicine, report that, in response to oligomers of Aβ or tau, astrocytes produce copious amounts of the tryptophan metabolite kynurenine, which scuppers glycolysis and...