LA JOLLA, Calif.—Even before the struggle of developing molecules that are safe and effective against therapeutic targets, drug developers face the issue of identifying those targets in the first place. There are about 25,000 proteins in the human body, but broad methods for determining which proteins are “druggable” are few. Researchers at The Scripps Research Institute...
Tag: <span>TSRI</span>
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TSRI tightens the noose on CMT
LA JOLLA, CA—Scientists at The Scripps Research Institute (TSRI) reported a week ago that they have shown a path to developing treatments for a degenerative nerve disease called Charcot-Marie-Tooth (CMT). The path targets the disease subtype CMT2D. As researchers report in the journal Nature Communications, it may be possible to reverse the disease by using a small molecule...
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Scripps Florida Scientists Uncover New Way to Defeat Therapy-Resistant Prostate Cancer
JUPITER, FL – December 29, 2016 – A new study led by scientists from the Florida campus of The Scripps Research Institute (TSRI) sheds light on a signaling circuit in cells that drives therapy resistance in prostate cancer. The researchers found that targeting the components of this circuit suppresses advanced prostate cancer development. The study,...