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Temperature-stable tuberculosis vaccine safe, prompts immune response in first-in-human trial
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Temperature-stable tuberculosis vaccine safe, prompts immune response in first-in-human trial

by NIH/National Institute of Allergy and Infectious Diseases Scanning electron micrograph of Mycobacterium tuberculosis bacteria, which cause TB. Credit: NIAID A clinical trial testing a freeze-dried, temperature-stable experimental tuberculosis (TB) vaccine in healthy adults found that it was safe and stimulated both antibodies and responses from the cellular arm of the immune system. The Phase...

How to make the tuberculosis vaccine more effective
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How to make the tuberculosis vaccine more effective

by Texas Biomedical Research Institute Researchers compared what happens when they give a saline solution (left), generic antibody (middle) or IL-10 blocker (right) with the BCG vaccine to mice. Mice given the IL-10 blocker were able to control TB infection in the lungs far better than the others. The dark pink spots show areas with...