September 12, 2024 by Institute for Research in Biomedicine (IRB Barcelona) Credit: Unsplash/CC0 Public DomainA team of researchers at IRB Barcelona has identified five independent factors that predict cancer patients’ response to checkpoint inhibitors (CPIs). The study, which has been published in Nature Genetics, validates these factors in more than 1,400 patients and diverse types...
News Release 9-Aug-2024 Researchers point to the urgency of developing innovative ways of using drugs that block blood vessel formation during cancer treatment Peer-Reviewed PublicationCactus Communications image: Inhibition of tumor angiogenesis is a universal approach for the treatment of tumors. This calls for the development of more effective next-generation anti-angiogenic drugs for advancing the treatment...
August 8, 2024 by China Anti-Cancer Association the game-changer in targeted tumor immunotherapyTumor immunotherapy targeting Tpex. Credit: Cancer Biology & Medicine Progenitor exhausted CD8+ T (Tpex) cells have emerged as a pivotal component in tumor immunotherapy due to their unique ability to self-renew and rapidly proliferate. These cells have shown promise in expanding and differentiating...
July 30, 2024 by Terasaki Institute for Biomedical Innovation Tissue-resident memory T cells impact non-small cell lung cancer immune microenvironment and prognosis. A machine learning model reveals the difference in the cancer subtypes. Credit: Terasaki InstituteAn extensive analytical study performed at the Terasaki Institute and published in Frontiers in Immunology highlights the crucial role of...
MAY 20, 2024 by Melissa Rohman, Northwestern University High-grade meningiomas are distinguished by regionally distinct intratumor immune infiltration, MAPK signaling, PI3K-AKT signaling, and cell proliferation. Credit: Amy B. Heimberger, MD, Ph.D. Investigators have discovered new mechanisms underlying the diversity of characteristics within a single tumor, as well as treatment resistance, in the most common type...
by Lauran Neergaard This combination of MRI scan images provided by the New England Journal of Medicine in March 2024 shows the progress of a glioblastoma patient who received CAR-T therapy which uses modified versions of T cells from a patient’s own immune system. Studies published by the New England Journal of Medicine on Wednesday,...
Patients diagnosed with esophageal cancer have low chances of survivalBut a test could detect signs of the cancer before it develops allowing treatment A vitamin pill-sized device could revolutionize the battle against a deadly throat cancer by diagnosing patients before they develop the disease. Patients diagnosed with esophageal cancer have just a 50 percent chance...
by University of Vienna Immunofluorescence image of the expression of PHGDH (red) and CD3 T cells (green) in cryosectioned AE17 mesothelioma. Credit: Zhengnan CaiA study by a scientific team from the University of Vienna and the MedUni Vienna, recently published in Cellular & Molecular Immunology, shows that the enzyme phosphoglycerate dehydrogenase (PHGDH) acts as a metabolic...
by University of Birmingham Credit: Cell Reports (2023). DOI: 10.1016/j.celrep.2023.113568 A highly aggressive common form of leukemia which is activated by mutations in signaling molecules is maintained by a web of regulatory proteins downstream of these signals. New research published in Cell Reports shows that a complex network of interacting genes activated by this altered signaling...
Donavyn Coffey February 17, 2023 UPDATED February 23, 2023 // Editor’s note: The headline of this article was changed from “New Cancer Screen, Same Issues: Physicians Confront Galleri Test” to better reflect the content of the article. In January 2022, Anthony Arenz, a 51-year-old living in Mesa, Arizona, breathed a small sigh of relief. The Galleri blood test,...
