August 8, 2024 by University of Bologna Top1ccs induce dynamic changes of hybrid levels at specific genomic sites in HCT116 cells. Credit: Science Advances (2024). DOI: 10.1126/sciadv.adm8196A research group at the University of Bologna has identified, for the first time, the specific location and genomic context where DNA breaks occur due to the inhibition of...
Tag: <span>tumor cell</span>
Researchers develop ‘on-demand’ whole tumor cell vaccine against cancer
by Chinese Academy of Sciences Strategy of using photothermal nanoparticle-based whole tumor cell vaccine (LN-TCV) for on-demand near-infrared (NIR) manipulation of immune responses against cancer. Credit: MENG Jiaqi Based on non-invasive, easy-to-manipulate near-infrared (NIR) laser irradiation, researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences and the University of the Chinese Academy of...
Moffitt researchers identify a mechanism controlling tumor cell recognition by immune cells
The STING signaling pathway induces an inflammatory response and tumor cell recognition H. LEE MOFFITT CANCER CENTER & RESEARCH INSTITUTE TAMPA, Fla. (Nov. 1, 2019) – Immunotherapy has become a standard treatment approach for several types of cancer, including melanoma. However, tumors can escape immune cell detection even with the use of immunotherapies. In a...