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Newly discovered mechanism halts tumor cell replication
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Newly discovered mechanism halts tumor cell replication

August 8, 2024 by University of Bologna Top1ccs induce dynamic changes of hybrid levels at specific genomic sites in HCT116 cells. Credit: Science Advances (2024). DOI: 10.1126/sciadv.adm8196A research group at the University of Bologna has identified, for the first time, the specific location and genomic context where DNA breaks occur due to the inhibition of...

Researchers develop ‘on-demand’ whole tumor cell vaccine against cancer
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Researchers develop ‘on-demand’ whole tumor cell vaccine against cancer

by Chinese Academy of Sciences Strategy of using photothermal nanoparticle-based whole tumor cell vaccine (LN-TCV) for on-demand near-infrared (NIR) manipulation of immune responses against cancer. Credit: MENG Jiaqi Based on non-invasive, easy-to-manipulate near-infrared (NIR) laser irradiation, researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences and the University of the Chinese Academy of...

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Moffitt researchers identify a mechanism controlling tumor cell recognition by immune cells

The STING signaling pathway induces an inflammatory response and tumor cell recognition H. LEE MOFFITT CANCER CENTER & RESEARCH INSTITUTE TAMPA, Fla. (Nov. 1, 2019) – Immunotherapy has become a standard treatment approach for several types of cancer, including melanoma. However, tumors can escape immune cell detection even with the use of immunotherapies. In a...