by Rensselaer Polytechnic Institute A compound found in green tea stabilizes an anti-cancer protein known as the “guardian of the genome.” Credit: Rensselaer Polytechnic Institute An antioxidant found in green tea may increase levels of p53, a natural anti-cancer protein, known as the “guardian of the genome” for its ability to repair DNA damage or destroy...
In preclinical experiments, investigators restored p53 using synthetic mRNA nanoparticles, making lung and liver cancer cells susceptible to available cancer drugs BRIGHAM AND WOMEN’S HOSPITAL In preclinical experiments, investigators restored p53 using synthetic mRNA nanoparticles, making lung and liver cancer cells susceptible to available cancer drugs The tumor suppressor gene p53, also known as the...
Think of it as a cancer therapy zag instead of a zig. While many groups are developing cancer therapies to target proteins and pathways that are highly active in cancer cells, a team of investigators from Brigham and Women’s Hospital and Boston Children’s Hospital, with collaborators at Memorial Sloan Kettering Cancer Center, is taking a...
