by H. Lee Moffitt Cancer Center & Research Institute Credit: CC0 Public Domain Evolution within groups of tumor cells follows the principles of natural selection, as evolution in pathogenic microbes. That is, the diversity of cellular characteristics within a group leads to differences in the ability of cells to survive and divide, which leads to selection for cells...
TOKYO MEDICAL AND DENTAL UNIVERSITY VASH1 exerts anti-angiogenic effects through the inhibition of receptor endocytosis by ?Y-tubulin increases. VEGF and FGF2 induce endocytosis of their own receptors, VEGFR2 and FGFR1, respectively, along MTs. This is important for VEGF (FGF2)-signaling activation and pro-angiogenic effects. VASH1 induces the generation of ?Y-tubulin-rich MTs (excessive ?Y-tubulin levels), leading to...
by The University of Hong Kong This electron microscopic image of two Epstein Barr Virus virions (viral particles) shows round capsids—protein-encased genetic material—loosely surrounded by the membrane envelope. A research team at LKS Faculty of Medicine, The University of Hong Kong (HKUMed) reports that exosomes derived from Vδ2-T cells (Vδ2-T-Exos) can effectively control Epstein-Barr-virus-associated tumors and induce T-cell...
One of the key mechanisms that cancer cells use to avoid being detected by the patient’s immune system is to build a micro-environment that inhibits immune system activity. Specifically, the cancer cells stimulate specific immune cells to directly stop their attack on the cancer cells. Thus, in a very large proportion of cancer patients, these...
By Michael Irving September 13, 2020 Researchers have shown how to grow gold inside cancer cells in order to kill them Gold isn’t just a pretty face – it’s shown promise in fighting cancer in many studies. Now researchers have found a way to grow gold nanoparticles directly inside cancer cells within 30 minutes, which...
Two experimental drugs fight non-small cell lung cancer by affecting their blood vessels, oxygen levels, and other environmental factors UT SOUTHWESTERN MEDICAL CENTER FROM LEFT: DRS. RALPH MASON, LI LIU, AND YIHANG GUO, AND RESEARCHER JENI GERBERICH USED A NEW TOOL CALLED MULTISPECTRAL OPTOACOUSTIC TOMOGRAPHY TO EXAMINE NON-SMALL CELL LUNG CANCER TUMORS GROWING. DALLAS –...
Tumor cells in younger and female patients accumulate cancer-causing mutations that are more poorly presented to the immune system, better enabling tumors to escape detection and clearance UNIVERSITY OF CALIFORNIA – SAN DIEGO DUE TO A PROCESS KNOWN AS IMMUNO-EDITING, YOUNGER AND FEMALE PATIENTS WITH CANCER HAVE CANCER-CAUSING GENETIC MUTATIONS THAT ARE LEAST VISIBLE TO...
By Benedette Cuffari, M.Sc. Reviewed by Emily Henderson, B.Sc. By definition, encephalitis is the inflammation of the brain. The causes of infectious encephalitis can be viral, bacterial, fungal, protozoal, or helminthic; however, about 70% of encephalitis cases are viral in etiology. Types of encephalitis Encephalitis can be characterized as either primary or secondary. Whereas primary...
by University of Calgary Researchers with the Snyder Institute for Chronic Diseases at the Cumming School of Medicine (CSM) have discovered which gut bacteria help our immune system battle cancerous tumors and how they do it. The discovery may provide a new understanding of why immunotherapy, a treatment for cancer that helps amplify the body’s...
by Institute for Research in Biomedicine – IRB Hypermutation is an unusual occurence that can lead to many nearby mutations at once, severely damaging our genetic material and potentially causing cancer. The best known type of local hypermutation, called a mutation shower or thunderstorm, is quite uncommon and it leads to many mutations accumulated in...
