by Johannes Angerer, Medical University of Vienna CAR-T cell therapy is a new and revolutionary weapon against cancer: T cells are isolated from the patient’s blood for genetic modification and then infused back into the patient to attack cancer cells. Researchers from the Medical University of Vienna have now determined why CAR-T cells do not...
by Cold Spring Harbor Laboratory Organoids of mouse pancreatic tumor cells grown “ex vivo,” outside the body. Organoids are used as a model system to study tumor biology and treatments. Credit: Tobiloba Oni, Tuveson lab/CSHL Scientists at Cold Spring Harbor Laboratory (CSHL) have found that they can stop the growth of pancreatic cancer cells by...
by Adrianna MacPherson, University of Alberta Researchers at the University of Alberta have found a way to deliver anti-cancer drugs with more precision, which could increase the effectiveness of many cancer treatments. U of A oncologist Frank Wuest altered the surface of nanoparticles, which are well suited to deliver drugs, with epidermal growth factor (EGF),...
by Dana-Farber Cancer Institute A novel liquid biopsy method can detect kidney cancers with high accuracy, including small, localized tumors which are often curable but for which no early detection method exists, say scientists from Dana-Farber Cancer Institute. The report in Nature Medicine suggests that if validated in larger trials and applied widely, the non-invasive...
by Yale University Yale researchers have discovered a “jamming signal” that blocks a powerful immune system stimulant called interleukin-18 (IL-18) from reaching tumors, including in cancers that are resistant to conventional immunotherapy treatments, they report June 24 in the journal Nature. The research team created a version of IL-18 that could not be jammed and...
by University of Cincinnati UC researchers have found a potential new combination therapy for breast cancer that would integrate use of the body’s immune system with targeted treatment for a particular protein that advances cancer. The study, published in the journal Cancer Research, a journal of the American Association for Cancer Research, provides data that...
by University Health Network Dr. Daniel De Carvalho and Krembil Brain Institute Medical Director Dr. Gelareh Zadeh collaborated to combine advanced technology with machine learning to develop a highly sensitive and accurate blood test to detect and classify brain cancers. Credit: UHN A simple but highly sensitive blood test has been found to accurately diagnose...
The study shows that the involvement of certain genes that predispose to cancer also affects the immune system, which could facilitate tumor growth. In the specific case of breast cancer, the involvement of the SH2B3 gene, corresponding to a lymphocyte protein, increases the predisposition to develop cancer. The idea that the immune system “monitors and...
by Whitney Slightham, Virginia Tech When the brain gets injured, star-shaped brain cells called astrocytes come to the rescue. In the case of glioma—the most common type of primary brain tumor—this protective action comes at a price. A new study published in Neurochemistry International reveals that gliomas alter astrocytefunction, which normally prevents the brain from...
FROM NEOSCOPE: SCIENTISTS FOUND THAT DAILY MARIJUANA USE ALLOWED SPECIFIC CANCER CELLS TO GROW UNCONTROLLABLY. BY VICTOR TANGERMANN A new study by researchers at the University of California San Diego School of Medicine found that THC — the stuff in cannabis that makes you high — can accelerate the growth of tumors in patients with...
