by Justin Jackson , Medical Xpress Credit: Unsplash/CC0 Public Domain A collaboration of researchers led by Emory University Rollins School of Public Health, Atlanta, is urging caution when prescribing off-label glucose-lowering drugs to individuals with type 1 diabetes (T1D). Both glucagon-like peptide-1 receptor agonists (GLP-1RA) and sodium-glucose cotransporter 2 (SGLT2) inhibitors have shown significant benefits...
Tag: <span>type 1 diabetes</span>
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Stem cell therapy reverses type 1 diabetes in world first
Credit: Cell (2024). DOI: 10.1016/j.cell.2024.09.004 A groundbreaking discovery has recently brought hope to millions of people living with type 1 diabetes around the world. In a world first, scientists have successfully used stem cell therapy to reverse type 1 diabetes in a woman. This achievement is being hailed as a major medical breakthrough, as it offers a potential cure...
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Research suggests a new strategy for people with type 1 diabetes to lower blood sugar after exercise
(A) Twenty-four-hour post-exercise continuous glucose monitoring (CGM). Each grey line represents 1 participant’s CGM trace for the 24-hour post-exercise period. (B) Comparison of 24-hour post-exercise median sensor glucose. Credit: Canadian Journal of Diabetes (2024). DOI: 10.1016/j.jcjd.2024.05.001 Adults with type 1 diabetes should perform aerobic cooldowns to manage high blood sugar after intense exercise where glucose levels might rise,...
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Bacterial infections could be trigger for type 1 diabetes, new research suggests
September 18, 2024 by Cardiff University Graphical abstract. Credit: Journal of Clinical Investigation (2024). DOI: 10.1172/JCI164535For the first time, scientists have found that proteins from bacteria can trigger the immune system to attack insulin-producing cells, leading to the development of type 1 diabetes. The new research showed that killer T-cells—a type of white blood cell...
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Children less likely to have type 1 diabetes if mother has condition than if father is affected, study finds
July 26, 2024 by Diabetologia Credit: Pixabay/CC0 Public DomainNew research to be presented at this year’s Annual Meeting of the European Association for the Study of Diabetes (EASD; Madrid, 9–13 September) shows that a child is almost twice as likely to develop type 1 diabetes (T1D) if their father has the condition, than if their...
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For type 1 diabetes distress, focus first on managing emotions
NEWS RELEASE 10-JUN-2024 Peer-Reviewed PublicationUNIVERSITY OF CALIFORNIA – SAN FRANCISCO FOR IMMEDIATE RELEASE Media Contact: Jess Berthold (628) 399-0432 [email protected] Subscribe to UCSF News For Type 1 Diabetes Distress, Focus First on Managing EmotionsVirtual, emotion-centered program cuts distress in half after one year, while also improving patients’ glucose control. The most effective way to reduce the...
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Study links small pancreas size to faster progression to stage 3 type 1 diabetes
by Vanderbilt University Medical Center Graphical Abstract. Credit: Diabetes Care (2023). DOI: 10.2337/dc23-1681A multicenter, longitudinal study, co-led by investigators at the Vanderbilt Diabetes Research and Training Center (DRTC), has discovered that a small pancreas size predicts a faster progression to stage 3 type 1 diabetes (T1D), the point at which clinical diagnosis occurs. The team also...
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New model links RNA editing glitch to early-stage type 1 diabetes
Hebrew University of Jerusalem Hebrew University study proposes a new model suggesting that disrupted RNA editing within pancreatic beta cells might initiate an inflammatory response akin to early-stage type 1 diabetes. This new perspective challenges the long-held belief of viral involvement, offering potential implications for treatments and cures. A recent study by researchers at the...
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Gut microbes may determine patients’ response to a drug that delays onset of type 1 diabetes
by Delthia Ricks , Medical Xpress Teplizumab delays type 1 diabetes (T1D) in at-risk individuals in TN10 trial, but participants respond differently to the treatment. Systemic, non-pathogenic antibody responses to gut bacteria can be quantified by anti-commensal antibody (ACAb) assay. Individuals with higher IgG2 responses to specific gut bacteria are more likely to get early...
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World-first human trial finds arthritis drug can suppress progression of type 1 diabetes
by St Vincent’s Institute of Medical Research Credit: CC0 Public Domain Researchers at St Vincent’s Institute of Medical Research (SVI) in Melbourne have shown that a commonly prescribed rheumatoid arthritis drug can suppress the progression of type 1 diabetes. The world-first human trial, published in the New England Journal of Medicine and led by SVI’s Professor...