by University of Basel Credit: Pixabay/CC0 Public Domain The heart disease arrhythmogenic cardiomyopathy can lead to sudden death, particularly affecting young athletes. Researchers at the University of Basel have now genetically modified mice, which develop a similar disease to that found in humans. This allowed the team to identify previously unknown mechanisms and potential therapeutic...
by Jennifer Lee, The Children’s Hospital of Philadelphia Credit: CC0 Public Domain Researchers at Children’s Hospital of Philadelphia (CHOP) have discovered a new part of the regulatory cascade responsible for silencing fetal hemoglobin in adult cells. The findings, published today in Nature Genetics, refine scientists’ understanding of the process that turns fetal hemoglobin “off” and adult...
by Laurel Kelly Credit: CC0 Public Domain Sickle cell disease, which is a group of inherited red blood cell disorders, affects approximately 100,000 people in the U.S., according to the Centers for Disease Control and Prevention. September is National Sickle Cell Awareness Month, which makes this a good time to learn about two of the...
UNIVERSITY OF MISSOURI-COLUMBIA IMAGE: YVES CHABU CREDIT: UNIVERSITY OF MISSOURI In the fight against cancers, activating mutations in the RAS family of genes stand in the way of finding viable treatment options. Now, scientists at the University of Missouri and Yale University have discovered that one of these mutations — oncogenic RAS or RASV12 —...
