Tag: <span>Unintended Mutations</span>

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CRISPR Gene Editing Can Cause Hundreds of Unintended Mutations

Structure of the gene editing enzyme Cas9 interacting with guide RNA and DNA (PDB ID: 4OO8). Source: Gabriel Velez (Mahajan Lab) As CRISPR-Cas9 starts to move into clinical trials, a new study published in Nature Methods has found that the gene-editing technology can introduce hundreds of unintended mutations into the genome. “We feel it’s critical that the...