By Dr. Chinta Sidharthan Reviewed by Susha Cheriyedath, M.Sc. Jul 2 2024 In a recent study published in the journal Nature Aging, a team of researchers used a large dataset consisting of participants of European ancestry from the United Kingdom (U.K.) Biobank to explore the genetic underpinnings of the biological age gap or BAG, a...
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Protein discovery could improve type 2 diabetes treatment
by University of Melbourne A world first discovery of how a protein works in the liver could lead to a more effective type 2 diabetes drug. The University of Melbourne-led study found that the SMOC1 protein, which is naturally produced by the liver, can decrease blood glucose levels. An engineered form of SMOC1 could therefore...
Failed Alzheimer’s drugs given new life after human gene discovery
By Rich Haridy August 19, 2020 A new study is questioning whether potential Alzheimer’s treatments previously found to be ineffective in human trials should be re-examined, after the discovery of a specific gene that can inhibit a therapy’s efficacy is only present in 75 percent of people. The long-standing cholinergic hypothesis for Alzheimer’s disease suggests...
There was a crooked man: Scoliosis and the deep history of the brain’s inner sanctum
by John Hewitt , Medical Xpress Lurking just beneath the surface of just about every common nursery rhyme is a complex record of times long gone. For example, the “crooked man” who “laid a crooked sixpence upon a crooked style” was none other than the great 17th-century Scot General Sir Alexander Leslie. The crooked stile...
Scientists identify gene linked to thinness that may help resist weight gain
by Cell Press While others may be dieting and hitting the gym hard to stay in shape, some people stay slim effortlessly no matter what they eat. In a study publishing May 21 in the journal Cell, researchers use a genetic database of more than 47,000 people in Estonia to identify a gene linked to...