Tag: <span>Urate transporter</span>

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Urate transporter structures reveal the mechanism behind important drug target for gout
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Urate transporter structures reveal the mechanism behind important drug target for gout

September 9, 2024 by St. Jude Children’s Research Hospital Cryo-EM structures of human URAT1 in different functional states. Credit: Cell Research (2024). DOI: 10.1038/s41422-024-01023-1Scientists at St. Jude Children’s Research Hospital have used cryo-electron microscopy to generate ten structures of URAT1, a protein linked to gout. Gout is a type of arthritis caused by excess urate...