JOHANNES GUTENBERG UNIVERSITAET MAINZ IMAGE: SANS is essential for the release of tri-snRNPs from the Cajal bodies and their transfer to the nuclear speckles. There the spliceosome is assembled and subsequently activated. Therefore, SANS plays a crucial role in correct pre-RNA splicing as a whole. CREDIT: ILL./©: UWE WOLFRUM Human Usher syndrome (USH) is the...
