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ALS and frontotemporal dementia show origins in utero, according to new study
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ALS and frontotemporal dementia show origins in utero, according to new study

by Cristy Lytal, Keck School of Medicine of USC Grpahical abstract. Credit: Cell Reports (2023). DOI: 10.1016/j.celrep.2023.112983 Even though neurodegenerative diseases often strike in middle age or later, patients could have structural differences in their brains that arise before birth. In a new study in Cell Reports, USC stem cell scientists used both patient-derived nerve cells and laboratory mice...

Rare, deadly genetic disease successfully treated in utero for first time
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Rare, deadly genetic disease successfully treated in utero for first time

by University of California, San Francisco Patient Ayla Bashir. Credit: University of California, San Francisco Using a protocol developed at UC San Francisco, physicians have successfully treated a fetus with a devastating genetic disorder for the first time, and the child is now thriving as a toddler, a case study in the New England Journal of...