A new research paper was published in Aging (listed by MEDLINE/PubMed as “Aging (Albany NY)” and “Aging-US” by Web of Science) Volume 15, Issue 23, entitled, “Angelica gigas extract inhibits acetylation of eNOS via IRE1α sulfonation/RIDD-SIRT1-mediated posttranslational modification in vascular dysfunction.” Angelica gigas NAKAI (AG) is a popular traditional medicinal herb widely used to treat...
Tag: <span>vascular disease</span>
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Study identifies a new potential target for treating vascular disease
by Elsevier A new study shows that when fragile-X related protein-1 (FXR1) is absent, vascular smooth muscle cells (VSMC) proliferate more slowly, become senescent, and scar tissue (neointima) development is reduced. Therefore, drugs targeting FXR1 may treat vascular proliferative diseases. Credit: The American Journal of Pathology Vascular diseases, including myocardial infarction, stroke, renal failure, and peripheral vascular...
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Transdifferentiation: Going straight to the source of vascular disease
by University of Tsukuba Credit: Christoph Burgstedt/Shutterstock Vascular diseases such as atherosclerosis, pulmonary hypertension, and cardiac fibrosis are associated with a reorganization of the structure of blood vessels. Researchers led by the University of Tsukuba have demonstrated transdifferentiation, an important process by which this reorganization occurs that holds promise for future treatments for vascular diseases. Blood vessels are...
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Favine protein potentially protects against vascular disease
by Osaka University Graphical abstract. Credit: iScience (2022). DOI: 10.1016/j.isci.2022.105252 Atherosclerosis, the clogging of the arteries with fatty plaques, is a major cause of death worldwide. Human atherosclerosis often involves calcification (or a build-up of calcium) in the arteries, and thrombosis, where a blood clot (or “thrombus”) blocks the blood vessel. Studies of atherosclerosis have been hindered...
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Researchers may have found the missing link between Alzheimer’s and vascular disease
by Columbia University Irving Medical Center Diagram of the brain of a person with Alzheimer’s Disease. Credit: Wikipedia/public domain. For more than 20 years, scientists have known that people with hypertension, diabetes, high cholesterol, or obesity have a higher likelihood of developing Alzheimer’s disease. The conditions can all affect the brain, damaging blood vessels and leading...
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Powerhouse-pruning protein may also aid new blood vessel growth in vascular disease
MEDICAL COLLEGE OF GEORGIA AT AUGUSTA UNIVERSITY IMAGE: DR. MASUKO USHIO-FUKAI CREDIT: MICHAEL HOLAHAN, AUGUSTA UNIVERSITY AUGUSTA, Ga. (April 4, 2022) – A protein that helps keep our cell powerhouses working at a premium appears to also help make energy rapidly available when it’s time to make new blood vessels. It’s called glycolysis, which quickly converts the...
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Eye provides clues to insidious vascular disease
UNIVERSITY OF BONN IMAGE: WHEN THE VESSELS ARE PHOTOGRAPHED THROUGH THE LENS OF THE EYE, NEURONAL NETWORKS CAN DETECT CERTAIN DISEASES ON THE BASIS OF THE IMAGES. CREDIT: MUELLER, S. UND WINTERGERST, M.W.M. ET AL. MULTIPLE INSTANCE LEARNING DETECTS PERIPHERAL ARTERIAL DISEASE FROM HIGH-RESOLUTION COLOR FUNDUS PHOTOGRAPHY. SCI REP 12, 1389 (2022) Researchers at the...
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People who eat more fish have fewer signs of vascular disease in the brain
by Alzheimer’s Research UK Credit: Unsplash/CC0 Public Domain Researchers in France have found a link between eating more fish and a lower risk of vascular brain disease. Vascular brain disease involves damage to blood vessels in the brain and is a risk factor for vascular dementia and stroke. The research is published today in the...
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Predicting relapses in patients with autoimmune vascular disease
Patients with an autoimmune disorder called antineutrophil cytoplasmic antibody-associated vasculitis produce antibodies that damage blood vessels in the body. In some cases, patients’ antibodies target a protein called myeloperoxidase. New research published in Arthritis & Rheumatology indicates that for patients in remission, reappearance of antibodies against myeloperoxidase is a sign that patients will experience a relapse of...