In a rat model, the discs became stiffer and changed shape earlier than normalPeer-Reviewed Publication UNIVERSITY OF CALIFORNIA – SAN DIEGO THE HIERARCHICAL STRUCTURE OF THE INTERVERTEBRAL DISC (APPROXIMATELY 45–55 MM DIAMETER IN THE HUMAN LUMBAR SPINE AND 2.5–5 MM IN THE RAT COCCYGEAL SPINE) IS COMPOSED OF THE OUTER FIBER-REINFORCED ANNULUS FIBROSUS AND INNER...